高瑞
博士，特聘副研究员
工作及教育经历
2024.12-至今 成都大学，高等研究院，特聘副研究员
2021.09-2024.11 中山大学，化学学院，科研助理/博士后
2016.09-2021.06 中山大学，化学学院，环境化学，理学博士
2013.09-2016.06 成都理工大学，材料与化学化工学院，分析化学，理学硕士
2009.09-2013.06 2013.09-2016.06 成都理工大学，材料与化学化工学院，化学，理学学士
研究方向
1. 酶-多孔晶态框架的杂化功能材料设计
2. 纳米酶构建及其在环境分析和修复的应用
科研项目
1. 分级介孔金属有机框架材料共固定化漆酶-介体体系的构建及其降解磺胺类抗生素的研究，中国博士后基金面上项目，2022.10-2024.10, 8万元，主持
2. 成都大学人才引进启动项目，2024.12-2029.11，45万，主持
3. 产生长寿命有机自由基的有机半导体环境功能材料的设计及其在地表水污染控制中的应用，国家自然科学基金重点项目，2024.01-2028.12, 230万元，参与
4. 土壤环境中微塑料的分异机制研究，国家自然科学面上项目, 2019.01-2022.12， 61万元，参与
代表性论文
1. Gao R#, Kou X#, Tong L, Li Z.-W，Shen Y, He R, Guo L, Wang H, Ma X, Huang S, Chen G*, Ouyang G. Ionic liquid-mediated dynamic polymerization for facile aqueous-phase synthesis of enzyme-covalent organic framework biocatalysts. Angew. Chem. Int. Ed. 2024, 63, e202319876 (IF=16.1/Top期刊).
2. Guo L, He R, Chen G*, Wang H, Kou X, Huang W, Gao R *, Huang S*, Zhu F, Huang S*, Ouyang G*. A synergetic compartmentalization and pore-hydrophobization strategy for enhancing the stability and activity of enzymes simultaneously. J. Am. Chem. Soc. 2024, 2024, 146, 17189-17200 (IF=14.4/Top期刊).
3. Wang H, Kou X, Gao R*, Huang S, Chen G.*, Ouyang G. Enzyme-immobilized porous crystals for environmental applications. Environ. Sci. Technol. 2024, 58, 11869-11886 (IF=10.8/Top期刊).
4. Gao R, Zhong N, Tong L, Kou X, Huang W, Yang H, Huang S*, Wu J, Chen G *, Ouyang G. Mechanochemistry-guided reticular assembly for stabilizing enzymes with covalent organic frameworks. Cell. Rep. Phys. Sci. 2022, 3, 101153 (IF=7.9).
5. Wang H#, Gao R#, Liang W, Wei S, Zhou Y, Zeng F*. Assessment of BPA and BPS exposure in the general population in Guangzhou, China-Estimation of daily intakes based on urinary metabolites. Environ. Pollut. 2022, 315, 120375 (IF=7.6).
6. Gao R, Cui K, Liang W, Wang H, Wei S, Zhou Y, Zeng F*. Molecular weight-dependent adsorption heterogeneities of humic acid on microplastics in aquatic environments: Further insights from fluorescence spectra combined with two-dimensional correlation spectroscopy and site energy distribution analysis. J. Environ. Chem. Eng. 2022, 10, 108948 (IF=7.4).
7. Gao R, Ye N, Kou X, Shen Y, Yang H, Wu T, Huang S*, Chen G*, Ouyang G. Hierarchically mesoporous Ce-based MOFs with enhanced alkaline phosphatase-like activity for phosphorylated biomarker sensing. Chem. Commun. 2022, 58, 12720 (IF=4.3).
8. Gao R, Zhong N, Huang S*, Li S, Chen G*, Ouyang G. Multienzyme biocatalytic cascade systems in porous organic frameworks for biosensing. Chem. Eur. J. 2022, e202200074 (IF=3.9).
9. Gao R, Wang H, Abdurahman A, Liang W, Lu X, Wei S, Zeng F *. Insight into the hetero-interactions of 4-nonylphenol with dissolved organic matter: multiple spectroscopic methods, 1H NMR study and principal component analysis. RSC Adv. 2022, 12, 22416 (IF=3.9).
10. Gao R#, Kou X#, Huang S*, Chen G *, Ouyang G. Developing covalent organic framework biocatalysts through enzyme encapsulation. Chembiochem. 2024, 17, e202400339 (IF=2.6).
